tomkindlon , to AusCOVID19 group
@tomkindlon@disabled.social avatar

Plasma taurine level is linked to symptom burden & clinical outcomes in condition

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0304522

"Increase in taurine levels during the transition to convalescence were associated with a reduction in adverse events independent of comorbidities & acute severity"

Hospitalised patients.

@longcovid
@covid19 @auscovid19

tomkindlon , to longcovid group
@tomkindlon@disabled.social avatar

From the Netherlands

Whole blood transcriptome in long patients reveals association with lung function and immune response

https://www.jacionline.org/article/S0091-6749(24)00566-9/fulltext

"In this study we clustered the transcriptome of patients into two distinct clusters & showed differences in innate and adaptive immune activation and pulmonary function between those clusters"

Hashtags:
@longcovid

@covid19

tomkindlon , to NoVID
@tomkindlon@disabled.social avatar

A Holistic Analysis of Symptom Profiles among People with #LongCOVID -19 in India: A Prospective 1-Year Follow-Up Study

https://www.sciencedirect.com/science/article/pii/S2213398424001490

"Out of 350 [hospitalised] participants, 148 respondents (42.3%) recovered after 1 year of illness and 202 (57.7%) were still experiencing symptoms at the time of survey completion."

Hashtags:
@longcovid
#PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #PASC #COVIDBrain
@covid19 #Coronavirus
#COVID19 #COVID #SARSCoV2 @novid

tomkindlon , to longcovid group
@tomkindlon@disabled.social avatar

Nirmatrelvir-Ritonavir and Symptoms in Adults With Postacute Sequelae of Infection: The STOP-PASC RCT

https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2819901

"The results of this randomized clinical trial showed that a 15-day course of NMV/r in a population of patients with was generally safe but did not demonstrate a significant benefit for improving select PASC symptoms in a mostly vaccinated cohort with protracted symptom duration"

@longcovid

tomkindlon , to MECFS group
@tomkindlon@disabled.social avatar
ALT
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  • tomkindlon , to longcovid group
    @tomkindlon@disabled.social avatar

    New-ish research from Italy:

    Longitudinal Exploration of Cortical Brain Activity in Cognitive Fog: An EEG Study in Patients with and without Anosmia:

    Free full text:
    https://www.imrpress.com/journal/JIN/23/5/10.31083/j.jin2305105

    "The results revealed significant differences in the neurophysiological parameters of P300 & beta band rhythms in subjects affected by cognitive fog, and these alterations persist even 8 months after recovery from "

    @longcovid

    tomkindlon , to longcovid group
    @tomkindlon@disabled.social avatar

    Association between acquiring SARS-CoV-2 during pregnancy and post-acute sequelae of infection: RECOVER electronic health record cohort analysis

    https://t.ly/uisJz

    "SARS-CoV-2 infection acquired during pregnancy was associated with lower risk of development of at 30–180 days after incident SARS-CoV-2 infection in this nationally representative sample”

    @longcovid


    @covid19

    tomkindlon , to longcovid group
    @tomkindlon@disabled.social avatar

    The roles of the kynurenine pathway in neuropathogenesis

    https://link.springer.com/article/10.1007/s15010-024-02293-y

    Review article. "The sustained activation of the KP [kynurenine pathway], associated with cognitive impairments & chronic fatigue, underscores the potential of KP as a therapeutic target & as a possible biomarker for in future studies”

    @longcovid

    @covid19

    tomkindlon , to longcovid group
    @tomkindlon@disabled.social avatar

    The importance of including Long outcomes when developing novel treatments for acute COVID-19

    Free
    https://academic.oup.com/jid/advance-article/doi/10.1093/infdis/jiae270/7676685

    "In our review, we argue there are 7 compelling reasons to include measurements"

    @longcovid


    @covid19 @novid @auscovid19

    tomkindlon , to longcovid group
    @tomkindlon@disabled.social avatar

    A murine model of post-acute neurological sequelae following variant infection

    Free:
    https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1384516/full

    "our results suggest that infection in K18-hACE2 mice recapitulates the persistent clinical symptoms reported in patients”

    Hashtags:
    @longcovid


    @covid19 @auscovid19

    tomkindlon , to longcovid group
    @tomkindlon@disabled.social avatar

    Emerge Australia Research Digest | Issue 106
    https://www.emerge.org.au/researchdigest/research-digest-issue-106/

    3 out of the 4 papers look at groups after Covid infection; the 4th paper looks at a group after Epstein-Barr virus infection

    Hashtags:
    @longcovid

    @mecfs
    @covid19
    @novid

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  • ahimsa_pdx , to longcovid group
    @ahimsa_pdx@disabled.social avatar

    "COVID can cause new health problems to appear years after infection, according to a study of more than 130,000 patients"

    https://fortune.com/well/article/covid-cause-new-health-problems-years-after-infection/

    "With more than 130,000 patients, the study is by far the largest so far to track the progress of the virus over a full three-year period."

    @longcovid @mecfs

    ALT
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