"Increase in taurine levels during the transition to convalescence were associated with a reduction in adverse events independent of comorbidities & acute #COVID19 severity"
"When stratified by variant epoch, patients with early epoch Long COVID had persistently elevated peripheral pro-inflammatory cytokine levels when compared to later epoch #LongCOVID. (contd)"
"(Contd) Patients with Long COVID have similar clusters of symptoms across epochs, suggesting that the underlying pathology is independent of the peripheral cytokine signature."
"Nine observational studies containing 866,066 patients were included, in which nirmatrelvir-ritonavir and molnupiravir were evaluated in eight and two studies respectively, with both drugs evaluated in one study. Pair-wise meta-analysis showed that early oral antiviral drugs reduced PCC risk (RR 0.77, 95% CI 0.68–0.88)."
I have been on facebook. The things I have seen. Oh gods the things I have seen!
I'm playing here, but I've been on the precipice of an anxiety attack for about 45 minutes. In an autoimmune neurological illness group (so subtle, so not identifying) someone tested positive for Covid19 today and wanted our input on how it was with our flavor of illness and what we did.
Many of us got Paxlovid ASAP, thank fucking gods. But the rest. One of us rubbed horse dewormer on their feet. Several of us believed our doctors when they told us Paxlovid was only to decrease our current visible symptoms so didn't bother with it. One of us went to work and bragged about how they infected their entire small company. Very few of us know what airborne means. Most of us seem to get our news from FOX.
We are all going to die. This is me, one the sidewalk, with a sign. The world is ending. Deliberate ignorance rules.
The misinformation people will spread is unbelievable. I'm not so bothered about the horse dewormer (that came with valuable advice: get the topical, not the pills, FFS) because I assume most of us know that's bananas. But the Paxlovid stuff bothers me a lot.
Paxlovid is an antiviral and its purpose is to prevent the duplication and spread of viral particles, therefore hopefully preventing long-covid, hospitalization, and death. If you need to treat your stuffy head fever get some damn Nyquill and tell your doctor the same. (Preaching to the choir over here on Fedi and it feels so good.)
FOX is telling people that Paxlovid is a lie because it doesn't treat long-covid. It was never meant to. Long-covid is a compilation of a shit ton of damage and illnesses, none of which an antiviral would help with.
One of us in the group is in a snit now because she was wrong about all of her assertions and she got caught spreading the illness. Boo hoo, bitch.
"Out of 350 [hospitalised] participants, 148 respondents (42.3%) recovered after 1 year of illness and 202 (57.7%) were still experiencing symptoms at the time of survey completion."
With this week's data, we're seeing plenty of Covid at all three county sites. Let's start with the West Point (WSPT) sewage treatment plant: the Sars-CoV-2 7-day rolling average more than doubled since last week. The last 7DRA number was calculated on 6/4.
WSPT is one of three King County(-ish) sewersheds in this dataset. You can find overviews, individual sewershed results, and a breakdown of variants for the state wastewater surveillance program, along with other metrics like case counts and hospitalizations for Covid-19 and other respiratory illnesses, at https://doh.wa.gov/data-and-statistical-reports/diseases-and-chronic-conditions/communicable-disease-surveillance-data/respiratory-illness-data-dashboard#WasteWater. If you go to the page and click "learn more" in the statewide view tab, you can find out lots of details about how these data are calculated and how to interpret them. The dashboard gets updated every Wednesday (generally).
Note: when the state switched over to new data providers in September, they also removed the previous historical data from the graphical interface. That's because the two providers used different methodologies that made direct comparisons difficult. Unfortunately, it also removed valuable context for interpreting the results. So, keep in mind we're just seeing what happened in September 2023 until now.
What repeated #COVID19 infections are doing to us:
On the left is data from the UK showing the number of people economically inactive due to long-term sickness. It fell for two decades and has exploded to record levels since the pandemic.
On the right is the US civilian labor force with a disability. It stayed steady for two decades and has exploded to record levels since the pandemic.
Both are at their record highs, and both still trend up. We're done with COVID, but it's not done with us.
"(Contd) While pacing was an essential skill for many, it was a constant balancing act , that also came at a cost on their productivity, satisfaction, and overall feelings of fulfillment"
"A notable feature of episodic disability in the context of Long COVID in this study was PESE or PEM which transcended physical, cognitive and mental-emotional dimensions, highlighting the ability of the framework to encompass critical features of disability experienced in the context of #LongCOVID"
4/
"Frequencies of new onset symptoms (in #PostCovid)
Among participants with #LongCOVID, the most common symptoms were post-exertional malaise (87%), fatigue (85%), brain fog (64%), dizziness or lightheadedness (62%), GI (59%), & palpitations (57%)."
🇪🇸Spain: Thousands of Taylor Swift concertgoers in Madrid have come down with COVID-19 after Eras Tour.
"One specific X account, known for being a hub for Spanish Swifties, took a poll of their followers, asking if they had become sick with COVID-19 after one of Swift's concerts in Madrid. Of the 10,796 people who answered the poll online, 35%, or 3,780 of the concertgoers said they had."
🗣 📢 IT'S FINALLY #Bday4Liza SO HAPPY BIRTHDAY TO ME!
given it’s my first surviving cancer and a pandemic, am spending it in the exotic landscape of Bellevue hospital waiting to get a friggin’ #COVID19 booster shot.
Some #COVID19 concerned people: "I can't vote for Biden because he's been a terrible pandemic leader." I get it, but if you care about vaccines and public health, you'll keep Trump out of office.
What can Trump do about vaccines? More than you might think.
His new anti-vaccine persona could have far-reaching consequences if he’s elected to a second stint as president with far-reaching administrative powers.
Every election. Every race. Every Democrat. #VoteBlue