Persistent symptoms & clinical findings in adults with post-acute sequelae of #COVID19 / #postCOVID19 syndrome in the second year after acute infection: population-based, nested case-control study
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"This nested population-based case-control study demonstrates the majority of PCS cases do not recover in the second year of their illness, with patterns of reported symptoms remaining essentially similar, nonspecific & dominated by fatigue, exercise intolerance & cognitive complaints”
"When stratified by variant epoch, patients with early epoch Long COVID had persistently elevated peripheral pro-inflammatory cytokine levels when compared to later epoch #LongCOVID. (contd)"
"(Contd) Patients with Long COVID have similar clusters of symptoms across epochs, suggesting that the underlying pathology is independent of the peripheral cytokine signature."
Mom was discharged, after she was stabilized, post day surgery/liver biopsy. She's going to rest in bed for rest of day when we get home. No strenuous physical activity for one week.
I had to ask almost all hospital medical staff, working with us today, to please put their masks on before coming near us. My handmarked mask helped with having no pushback on my mandatory mask-up request. Everyone I asked, stared at it, before grabbing masks & putting them on.
"Nine observational studies containing 866,066 patients were included, in which nirmatrelvir-ritonavir and molnupiravir were evaluated in eight and two studies respectively, with both drugs evaluated in one study. Pair-wise meta-analysis showed that early oral antiviral drugs reduced PCC risk (RR 0.77, 95% CI 0.68–0.88)."
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"Frequencies of new onset symptoms (in #PostCovid)
Among participants with #LongCOVID, the most common symptoms were post-exertional malaise (87%), fatigue (85%), brain fog (64%), dizziness or lightheadedness (62%), GI (59%), & palpitations (57%)."
It’s unethical that COVID is frequently left out of conversations about public transport accessibility. Many disabled and higher risk people haven’t been able to access public transport for years due to the lack of masks and clean air. This is a huge equity issue.
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“People are developing new-onset disease as the result of an infection that they had 3 years ago,” says Ziyad Al-Aly, “It challenges the notion that these viruses are sort of self-contained or that after the acute phase, they become inconsequential.”
"And cumulatively, at three years, #longCOVID results in 91 disability-adjusted life years (DALY) per 1,000 people—DALYs being a measure of years lost to poor health or premature death. That is a higher incidence than either heart disease or cancer."
"Risks for post-acute sequelae declined over the years, but substantial residual risk remained in the third year, leading to 252.8 sequelae per 1,000 persons& 90.0 DALYs per 1,000 persons”
It occurred to me today that even though over 1 million Americans have died from Covid, we have no national memorial or national day day of mourning and how the powers that be have decided to memory hole the whole thing and how wrong this is.
The way the mainstream media covers Bird Flu is wild. It's like a watchman who sees a giant ogre coming and says, "There's on ogre out there. But don't worry, he's walking the other way. Oop! He's walking this way, but he's probly headed somewhere else. Oh, ok, he's headed this way, but he probably won't eat anybody when he gets here. Ok, he's here, but so far he's only looking at folks hungrily. He's probably just window shopping. Ok, so now..." #avianflu#birdflu#CovidIsNotOver#uspolitics#media
Long #Covid Support:
Research Involvement Consultancy
"We make it easy to involve people with #LongCovid in your research and help ensure your study is relevant, robust and keeps the patient voice at the centre."
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"Our research advisers are all people with Long Covid who are trained in Patient Involvement in Research and have practical experience of being involved in various studies. Book a slot in one of our regular scheduled online advice sessions."