"Cognitive decline primarily manifested in individuals with severe COVID-19 during the initial year of infection, after which the rate of decline decelerated."
"The finding that patients with Long COVID show more comparable brain glucose metabolism to controls in the frontal cortex and basal ganglia subregions suggests that the pathophysiology of Long COVID fatigue may involve different biological systems beyond the central nervous system."
"Although evidence suggests persistent autoantibodies can be associated with post-#COVID symptoms,the clinical relevance of their presence seems modest at this stage”
“MENSA offers a unique antibody snapshot to reveal the underlying viral drivers in #longCOVID thus demonstrating the persistence of SARS2 and reactivation of viral herpes in 60% of PASC patients."
"Here we identify 679 diseases associated with an increased risk for severe #COVID_19 (n = 672) and/or #LongCOVID (n = 72) that span almost all clinical specialties and are strongly enriched in clusters of cardio-respiratory and endocrine-renal diseases."
"The largest proportion of Long COVID diagnoses occur among individuals with a first reinfection in the Delta epoch. The rate of Long COVID diagnoses has been increasing with each successive Omicron variant"
Press release:
"Brain inflammation triggers muscle weakness after infections: In fruit flies and mice, scientists ID possible way to block muscle fatigue in #longCOVID, other diseases"
“Physical, social, mental, and emotional stress can cause these abnormal reactions, and it doesn’t matter if the cause is an enjoyable activity like reading a novel or visiting friends.”
"In this work, an interventional method is developed to identify & remove the traveling microthrombi using targeted-magnetic microbubbles (TMMBs) & an interventional magnetic catheter”
New pre-print:
Circulating microclots are structurally associated with Neutrophil Extracellular Traps and their amounts are strongly elevated in long COVID patients
An HERV-W ENV transcription in atypical memory B cells linked to #COVID19 evolution & risk for #longCOVID can express the encoded protein from a ribosome readthrough of mRNA from chromosome X
"Results not only confirm HERV-W ENV RNA origin in these patients, but show for the first time how a defective HERV copy can be translated into a complete protein when specific factors make it possible at the ribosome level.”