on a New York Times article on a new, major National Academies report, "Long-Term Health Effects of #COVID19: Disability & Function Following #SARSCoV2 Infection"
Extract from comments by Dr Binita Kane in this popular Guardian article today:
"‘I could bench-press 100kg. Now, I can’t walk’: Lucy’s life with #longCovid ."
"Before the pandemic, Lucy Keighley ran a gym, worked as a personal trainer and went on gruelling, exhilarating runs. But after three and a half years of illness, she isn’t sure she will ever recover"
"The results revealed significant differences in the neurophysiological parameters of P300 & beta band rhythms in subjects affected by cognitive fog, and these alterations persist even 8 months after recovery from #Covid19"
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“We need to be much bolder and much more ambitious with our trials,” Al-Aly says. “At the glacial pace that they’re going, we’re unlikely to get any definitive answers for decades to come.”
"And cumulatively, at three years, #longCOVID results in 91 disability-adjusted life years (DALY) per 1,000 people—DALYs being a measure of years lost to poor health or premature death. That is a higher incidence than either heart disease or cancer."
Blood brain barrier disruption and glutamatergic excitotoxicity in post-acute sequelae of #SARSCOV2 infection cognitive impairment: potential biomarkers & a window into pathogenesis
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"We have undertaken a comprehensive proof-of-concept prospective case–control study to investigate parallel changes in blood brain barrier permeability, neurochemicals, & white matter microstructure changes in #PASC CI [cognitive impairment] patients"
"(Contd) In line with this assumed chronicity, 85% of patients reporting complaints two months after COVID-19 still reported symptoms one year after their symptom onset"
"we applied the advanced imaging technique [Diffusion Microstructure Imaging] to uncover microstructural changes after #COVID19 infection, with the observation of different patterns in a cohort of patients with and without PCC [Post-COVID-condition]"
The Australian ME/CFS & #LongCOVID (AusME) Registry is an online study of individuals aged 12yrs+ with ME/CFS and Long #COVID, as well as healthy volunteers