"The largest proportion of Long COVID diagnoses occur among individuals with a first reinfection in the Delta epoch. The rate of Long COVID diagnoses has been increasing with each successive Omicron variant"
@tomkindlon@longcovid@covid19@novid@novid
Surely this study just shows most clinical data is from severe infection? I don't believe that my own data and from similar other cases would have ever been recorded, leading to a systemic bias...
Press release:
"Brain inflammation triggers muscle weakness after infections: In fruit flies and mice, scientists ID possible way to block muscle fatigue in #longCOVID, other diseases"
@tomkindlon@longcovid@mecfs@covid19 anecdotal account: I've been on both classes of drugs (JAKS inhibitor and IL-6 inhibitor) for rheumatoid arthritis and didn't experience much affect on the ME/CFS. Tbh the TNF-a inhibitor that I'm on now has done a lot more, at least for brain fog and very slow physical improvements.
4/
Extract:
“There is little evidence to suggest that poor fitness is the explanation for PEM – the characteristic worsening of symptoms following exertion – which in many cases does not involve physical
activity at all …”
Neurologically triggered PEM can occur without exceeding a heart rate threshold and is not the result of ventilatory anaerobic threshold problems.
Heart rate-based pacing is helpful for PEM triggered by physical activity, not for PEM triggered by cognitive, sensory, or emotional exertion. The only thing that works for my neuro PEM is timers and carefully calibrating the types of activities I do.
@tomkindlon@longcovid@covid19@auscovid19 I have shared the invitation to the post Covid seminar, in the Swedish Facebook group for long Covid, as well in my normal Facebook flow.
This is a project I have been working on for a while.
Grateful to David Tuller and the local hosts: Vera Kindlon (Assoc trustee), Audrey Lodge, Ashling O’Leary & Michelle Dinn, Sarah Warde, Orla Ní Chomhraí (Assoc trustee) & Ruth Flood @roothflud . 👍
@tomkindlon
Interesting! Great to see a study confirm anecdotal/survey evidence. Though worth noting that the sample size was too small to make any direct call on CFS: only one person had CFS before getting covid.
2/
Post summarises this paper:
New Publication by Solve Ramsay Grant Researcher Dr. Deborah Duricka Studies Efficacy of Stellate Ganglion Block in Reducing Post-Exertional Malaise and Improving Sleep and Neurological Function
"Welcome to the 107th Emerge Australia Research Digest, where we delve into recent research and media releases shaping our understanding of ME/CFS and #LongCOVID..."
The summaries are also available in audio form at link
“The idea of rehabilitation will have to be completely rethought for this illness” – Qualitative results of an online survey on patients’ experiences with inpatient rehabilitation for #postCOVID19 condition ( #longCOVID )
'(50 %) reported that their state of health deteriorated, mainly because of strength or endurance training'
'learning strategies to avoid deterioration in their state of health due to overexertion, the so-called pacing, should be the core treatment goal for patients affected by PEM.'
"22.5% did not recover by 90 days post infection". "Recovery within 3 months was less likely in women and those with preexisting cardiovascular disease"
"No significant multivariable-adjusted associations [for non-recovery] were observed for age, educational attainment, smoking history, obesity, diabetes, chronic kidney disease, asthma, chronic obstructive pulmonary disease, or elevated depressive symptoms. Results were similar for reinfections"
"Passive transfer of IgG from patients to mice led to increased sensitivity & pain, mirroring patient-reported symptoms. Similarly, mice injected with IgG showed loss of balance & coordination, reflecting donor-reported dizziness"
Opinion piece asking why we overlook bad things, "especially in this scientific and technological age, when we’ve never been more capable of understanding and addressing them".