4/
Extract:
“There is little evidence to suggest that poor fitness is the explanation for PEM – the characteristic worsening of symptoms following exertion – which in many cases does not involve physical
activity at all …”
Applying for the #NDIS is soul destroying and they keep adding more paperwork and meetings and bullshit just to wear us down.
I submitted my application in April. I’d been working on it for a year. They generally tell you yes or no without 6 weeks. Instead I didn’t get a reply, I was told the application process has changed and they needed more goals and more meetings. First I was told it was optional, now I’m told it isn’t. Which one is it??
I look like this most days and they want more bloody meetings!?
Neurologically triggered PEM can occur without exceeding a heart rate threshold and is not the result of ventilatory anaerobic threshold problems.
Heart rate-based pacing is helpful for PEM triggered by physical activity, not for PEM triggered by cognitive, sensory, or emotional exertion. The only thing that works for my neuro PEM is timers and carefully calibrating the types of activities I do.
@mecfs@halcionandon@longcovid I haven't. I'm using 3x 600mg Acetylcysteine daily, which gives me Energy. And cold showers in the morning which helps mitigating symptoms.
Ok I see. Im glad it works for you. She recommends testing to see levels first and prefers pregnenolone in general from the Dr Myhill pages I read. I guess it depends on what you have going on.
There is also the small problem of DHEA being illegal in Australia & only available as a compounded prescription. The laws changed recently and I didn’t know. Not sure about pregnenolone.
Applying for the #NDIS is soul destroying and they keep adding more paperwork and meetings and bullshit just to wear us down.
I submitted my application in April. I’d been working on it for a year. They generally tell you yes or no without 6 weeks. Instead I didn’t get a reply, I was told the application process has changed and they needed more goals and more meetings. First I was told it was optional, now I’m told it isn’t. Which one is it??
I look like this most days and they want more bloody meetings!?
"In this work, an interventional method is developed to identify & remove the traveling microthrombi using targeted-magnetic microbubbles (TMMBs) & an interventional magnetic catheter”
New pre-print:
Circulating microclots are structurally associated with Neutrophil Extracellular Traps and their amounts are strongly elevated in long COVID patients
"Our study revealed that NETs may be a component of circulating FAM, suggesting that higher NETs formation promotes the stabilization of FAM in the circulation, leading to deleterious effects which (in part) may contribute to the symptoms of LC."
An HERV-W ENV transcription in atypical memory B cells linked to #COVID19 evolution & risk for #longCOVID can express the encoded protein from a ribosome readthrough of mRNA from chromosome X
"Results not only confirm HERV-W ENV RNA origin in these patients, but show for the first time how a defective HERV copy can be translated into a complete protein when specific factors make it possible at the ribosome level.”
"We found people with #longCOVID are using commercial fitness tracking technologies in unanticipated ways to collect data such as heart rate, number of steps and sleep quality”
“(Contd) These technologies were used to understand the enigmatic long COVID illness and manage symptoms through pacing energy through finding correlations between activities and their impact on their self-tracked data."
"our study establishes that patients with LCS [#LongCovid Syndrome] exhibit lower absolute and relative HRV values compared to controls, with peak VO2max emerging as a significant mediator in this relationship."