Holy Innocents' Cemetery - A medieval cemetery so overfilled, buildings were constructed around it, which were then filled with exhumed bones up to the rafters to make room for more bodies. ( en.wikipedia.org )
Heartbeat in the Brain - Lost 1970 documentary in which the director/subject drills a hole in her forehead with a dentist's drill ( en.wikipedia.org )
John Murray Spear - Minister who attempted to create an electrically-powered metallic machine god which was dubbed "The New Motive Power" ( en.wikipedia.org )
A Hole in My Heart - 2004 film notable for its explicit imagery, including close-ups of vaginal reconstruction surgery and a masturbation scene with a toothbrush ( en.wikipedia.org )
Trepanning - a surgical intervention in which a hole is drilled into the human skull. Evidence has been found in prehistoric human remains from Neolithic times onward ( en.wikipedia.org )
Katherine Knight: An Australian woman who, in 2000, murdered, skinned, dismembered and cooked her husband, and attempted to feed him to his adult sons https://en.wikipedia.org/wiki/Katherine_Knight...
Natalia Grace: Inspired by the plot of the 2009 horror film Orphan, Natalia's adoptive parents legally changed her real age so she would become an "adult", at which point they promptly abandoned her Natalia was born in Ukraine in 2003, and was diagnosed with a rare form of dwarfism. More or less immediately, she was given up for adoption....
JonBenét Ramsey - American child beauty queen killed at the age of six in her family's home with a long handwritten ransom note found in the scene ( en.wikipedia.org )
Jetpack man - Unknown person or object that has been observed flying what appears to be an unauthorized jetpack around LA ( en.wikipedia.org )