Adobe lightroom (with its multi-device editing and catalogue management - even when only using its cloud for smart previews).
Hardware support for music. NI Maschine is a non-starter. Most other devices are, at best, a 'hope it works' but are most definitely unsupported.
Music software. You can hack your way into getting a lot of your paid modules to work, but it is certainly not supported.
Wine is 'fun'(?), but it's a game of whack-a-mole chasing windows' tail and will never allow everything to run. Either way it's not 'supported.
Businesses any any size tend to eschew SW/HW that doesn't have formal support. (things like RHEL are most definitely supported as servers and orgs certainly leverage it).
I keep installing Linux hoping I can get a sufficient amount stuff to work "well enough" to move on from windows but it's just not to be (yet). Hope it changes, but it'll require buy-in from commercial product developers. I hope as Linux continues to grow a foothold in desktop installs, a critical mass will be reached, commercial devs take notice and it'll be easier to switch.
For now, I'm stuck with Windows and WSL. (But I am not happy with Windows' direction).