While she's not free of blame for losing, the primary opposition party candidate colluding with a foreign power to manipulate the election definitely had more of an effect on the result than anything she did. DNC emails poisoning the progressives support for her while Comey's investigation into being made public (because of Republicans leaking it) eroded away the support of independents and undecided voters.
In an alternate world whete the RNC emails got leaked and Comey's investigation of Trump got leaked to the public and there is no way Trump wins and likely is in handcuffs before Jan 20 2017