You can't go back home to your family, back home to your childhood ... back home to a young man's dreams of glory and of fame ... back home to places in the country, back home to the old forms and systems of things which once seemed everlasting, but which are changing all the time – back home to the escapes of Time and Memory.
It might get better later on, once you accept that the world has moved on, your old room is now an office, your parents are becoming old people, and time is passing. At some point you start getting nostalgic about the things that remained the same in a different way - or at least I did. But Wolfe is still right - it's not home any more.