First Map of Human Limb Development Reveals Unexpected Growth Processes and Explains Syndromes Found at Birth ( www.sanger.ac.uk )

Scientists reveal unprecedented insights into human limb development, including the many intricate processes that govern their formation.

Human fingers and toes do not grow outward; instead, they form from within a larger foundational bud, as intervening cells recede to reveal the digits beneath. This is among many processes captured for the first time as scientists unveil a spatial cell atlas of the entire developing human limb, resolved in space and time.