Been rocking Pop! with a 3080 for about 3 months with only a few minor gripes. Darktide had some weird tiny lag in it somewhere that I couldn't nail down but every other game I've played has worked just fine. And for some reason if I connect to mullvad using their app before opening Firefox, it'll lag out for 10-15 secs.
Everything else has been rock solid. I'd prefer KDE to Gnome, but with Dash to Panel, the Pop Gnome is good enough for now. Cosmic should be out relatively soon. I tinkered with Nobara and KDE plasma 6 for a few days but it was nowhere near as stable, so I came right back to Pop.