Currently, Intel x86_64 is the only supported host platform.
AMD will most likely work too but is considered experimental at the moment.
Linux is required as a host operating system for building and running VirtualBox KVM.
Starting with Intel Tiger Lake (11th Gen Core processors) or newer, split lock detection must be turned off in the host system. This can be achieved using the Linux kernel command line parameter split_lock_detect=off or using the split_lock_mitigate sysctl.